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排序方式: 共有474条查询结果,搜索用时 171 毫秒
61.
Szeto KC Lillerud KP Tilset M Bjørgen M Prestipino C Zecchina A Lamberti C Bordiga S 《The journal of physical chemistry. B》2006,110(43):21509-21520
A metal-organic framework (MOF) based on Pt, Y, and 2,2'-bipyridine-5,5'-dicarboxylate (BPDC), stable up to 400 degrees C, has been synthesized and characterized. In this MOF, the Pt centers are coordinated to Cl and the N atoms of the BPDC unit, giving a local environment similar to that found in a series of Pt-organic complexes with catalytic activity toward C-H bond cleavage of alkanes. This new material is a heterogeneous counterpart to the corresponding metal-organic complex. The structure, determined by single-crystal XRD data, is the repetition of three covalently bonded layers. These layers form a block, which is stacking as an (a)(b)(c) sequence along the crystallographic b-axis. Each layer contains the Pt-organic unit, while Y atoms represent the connection between adjacent layers. No covalent connection is present between layer (a) of a block and layer (c) of an adjacent block. EXAFS (BM29 at the ESRF) analysis supports the XRD data. As this MOF crystallizes under hydrothermal conditions, water acts both as solvent and as a direct ligand of Y. Accessibility to the metal centers is demonstrated by reversible water desorption/readsorption, as determined by TPA/TPD, FTIR, UV-vis, EXAFS, and XANES. Importantly, the results show that the as-synthesized material will not suffer a permanent loss in porosity upon solvent removal. In addition to water, methanol, ethanol, and acetonitrile can also access the internal void of the dehydrated phase. 相似文献
62.
Patrícia S. Peixoto Ildikó V. Tóth Luisa Barreiros Ana Machado Adriano A. Bordalo José L. F. C. Lima 《International journal of environmental analytical chemistry》2019,99(3):258-269
Fluoroquinolones are in the order of the day concerning environmental contamination through anthropogenic activities, resulting in increased risk for antibiotic resistance dissemination. In this context, accessible, low-cost analytical methods are required for implementation of comprehensive surveillance and screening schemes. In this work, we propose a down-scaled disk-based solid-phase extraction system from which the eluate can be first screened by miniaturized fluorimetric reading, followed by individual determination of target fluoroquinolones (ciprofloxacin, norfloxacin, and enrofloxacin) by liquid chromatography combined to tandem mass spectrometry. The fluorimetric measurement is based on the intrinsic fluorescence of fluoroquinolones. Disk-based retention was performed after sample acidification (pH 4.0) by mixed-mode cation exchange using polystyrene divinylbenzene sulphonated sorbent. Sample loading was precisely controlled in a dedicated flow system operating at 4.0 mL min?1. Different eluent compositions were tested, with elution performed by 1.00 mL of methanol-ammonium hydroxide (98:2, v/v), with subsequent reading of eluate in both detectors. Quantification was attained for 2–25 µg L?1 range, with LOD values at 1 µg L?1. The proposed approach was successfully applied to estuarine waters from the Douro River, with comparable results to a conventional SPE-LC-MS/MS procedure. 相似文献
63.
Eulogio J. Llorent-Martínez Pilar Ortega-Barrales Muhammad Zakariyyah Aumeeruddy Marcello Locatelli Adriano Mollica 《Analytical letters》2019,52(5):852-868
This study investigates into the pharmacological potential of three solvent extracts (ethyl acetate, methanol, and water) of two Ajuga species (Ajuga chamaepitys subsp. chia var. chia and Ajuga bombycina) based on their antioxidant activity and enzyme inhibitory effects along with establishing the phytochemical profile. Spectrophotometric and high-performance liquid chromatography–electrospray ionization–tandem mass spectrometry (HPLC–ESI–MSn) were used to determine the total and individual phytocompounds, respectively. Antioxidant potential was assessed using different assays such as DPPH, ABTS, CUPRAC, FRAP, phosphomolybdenum, and metal chelation. Enzyme inhibitory effects were studied against acetylcholinesterase, butyrylcholinesterase, tyrosinase, α-amylase, and α-glucosidase. The aqueous extract of both plants showed better ABTS scavenging, FRAP, and metal chelating activities. The methanol extracts displayed the highest tyrosinase inhibitory and antioxidant activity in the phosphomolybdenum assay while the ethyl acetate extracts of both plants showed better butyrylcholinesterase (BChE), α-amylase, and α-glucosidase inhibition. The total phenolic content was highest in the aqueous extract of A. chamaepitys while the methanolic extract of A. bombycina showed the highest flavonoid content. Identification by HPLC–ESI–MSn revealed the presence of some individual compounds including phenolic acids, flavonoids, iridoid glycosides, phenylethanoid glycosides, and other compounds. To conclude, both A. chamaepitys and A. bombycina can be considered as rich sources of phytocompounds to manage chronic diseases. 相似文献
64.
José Edgar Madriz Aguilar Carlos Romero Adriano Barros 《General Relativity and Gravitation》2008,40(1):117-130
We investigate, in the context of five-dimensional (5D) Brans–Dicke theory of gravity, the idea that macroscopic matter configurations
can be generated from pure vacuum in five dimensions, an approach first proposed by Wesson and collaborators in the framework
of 5D general relativity. We show that the 5D Brans–Dicke vacuum equations when reduced to four dimensions (4D) lead to a
modified version of Brans–Dicke theory in 4D. As an application of the formalism, we obtain two 5D extensions of 4D O’Hanlon
and Tupper vacuum solution and show that they lead two different cosmological scenarios in 4D. 相似文献
65.
Study of spatial inhomogeneity in inverted all‐polymer solar cells: Effect of solvent and annealing 下载免费PDF全文
Andrea Perulli Sandro Lattante Anna Persano Adriano Cola Massimo Di Giulio Marco Anni 《Journal of Polymer Science.Polymer Physics》2015,53(11):804-813
The efficiency optimization of bulk heterojunction solar cells requires the control of the local active materials arrangement in order to obtain the best compromise between efficient charge generation and charge collection. Here, we investigate the large scale (10–100 μm) inhomogeneity of the photoluminescence (PL) and the external quantum efficiency (EQE) in inverted all‐polymer solar cells (APSC) with regioregular poly(3‐hexylthiophene) (P3HT):poly(9,9‐dioctylfluorene‐co‐benzothiadiazole) (F8BT) active blends. The morphology and the local active polymer mixing are changed by depositing the active layer from four different solvents and by thermal annealing. The simultaneous PL and EQE mapping allowed us to inspect the effects of local irregularities of active layer thickness, polymer mixing, polymer aggregation on the charge generation and collection efficiencies. In particular, we show that the increase of the solvent boiling point affects the EQE non‐uniformity due to thickness fluctuations, the density non‐uniformity of rrP3HT aggregate phase, and the blend components clustering. The thermal annealing leads to a general improvement of EQE and to an F8BT clustering in all the samples with locally decrease of the EQE. We estimate that the film uniformity optimization can lead to a total EQE improvement between 2.7 and 6.3 times. © 2015 Wiley Periodicals, Inc. J. Polym. Sci., Part B: Polym. Phys. 2015 , 53, 804–813 相似文献
66.
67.
Josepha Yohanna de Jesus Eliane Santos de Carvalho Dantas Mairim Russo Serafini Paula dos Passos Menezes Juliana Cordeiro Cardoso Ricardo Luiz Cavalcanti Albuquerque-Jr Jivaldo do Rosário Matos Juliana Ferreira de Oliveira Irwin Rose Alencar de Menezes Francilene Amaral da Silva Adriano Antunes de Souza Araújo 《Journal of Thermal Analysis and Calorimetry》2016,123(3):2003-2012
68.
Laíse Oliveira Resende Ana Cristina Honorato de Castro Adriano O. Andrade João Marcos Madurro Ana Graci Brito-Madurro 《Journal of Solid State Electrochemistry》2018,22(5):1365-1372
Epidemiological studies have demonstrated an association between the risk of cardiovascular events and increasing C-reactive protein (CRP) concentration. This paper reports the development of an immunosensor for the assessment of the cardiovascular process using anti-C-reactive protein antibody immobilized onto a gold-printed screen electrode. Positive and negative human sera were successfully evaluated using electrochemical impedance spectroscopy (EIS), differential pulse voltammetry (DPV), and atomic force microscopy (AFM). EIS results show that, after the incubation with positive serum for myocardial infarction, the resistance increased about two times in relation to the negative serum. A linear range from 6.25 to 50 μg mL?1 and detection limit of 0.78 μg mL?1 using DPV were obtained. The immunosensor developed for the CRP detection using gold electrode revealed efficacy and a potential use for the diagnosis and monitoring of the progression of cardiovascular diseases. 相似文献
69.
MSPD procedure for determining buprofezin,tetradifon, vinclozolin,and bifenthrin residues in propolis by gas chromatography–mass spectrometry 总被引:1,自引:0,他引:1
dos Santos TF Aquino A Dórea HS Navickiene S 《Analytical and bioanalytical chemistry》2008,390(5):1425-1430
A simple and effective extraction method based on matrix solid-phase dispersion (MSPD) was developed to determine bifenthrin,
buprofezin, tetradifon, and vinclozolin in propolis using gas chromatography–mass spectrometry in selected ion monitoring
mode (GC–MS, SIM). Different method conditions were evaluated, for example type of solid phase (C18, alumina, silica, and Florisil), the amount of solid phase and eluent (n-hexane, dichloromethane, dichloromethane–n-hexane (8:2 and 1:1, v/v) and dichloromethane–ethyl acetate (9:1, 8:2 and 7:3, v/v)). The best results were obtained using 0.5 g propolis, 1.0 g silica as dispersant sorbent, 1.0 g Florisil as clean-up sorbent,
and dichloromethane–ethyl acetate (9:1, v/v) as eluting solvent. The method was validated by analysis of propolis samples fortified at different concentration levels
(0.25 to 1.0 mg kg−1). Average recoveries (four replicates) ranged from 67% to 175% with relative standard deviation between 5.6% and 12.1%. Detection
and quantification limits ranged from 0.05 to 0.10 mg kg−1 and 0.15 to 0.25 mg kg−1 propolis, respectively. 相似文献
70.
Cardoso CL de Moraes MC Guido RV Oliva G Andricopulo AD Wainer IW Cass QB 《The Analyst》2008,133(1):93-99
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) plays an important role in the life cycle of the Trypanosoma cruzi, and an immobilized enzyme reactor (IMER) has been developed for use in the on-line screening for GAPDH inhibitors. An IMER containing human GAPDH has been previously reported; however, these conditions produced a T. cruzi GAPDH-IMER with poor activity and stability. The factors affecting the stability of the human and T. cruzi GAPDHs in the immobilization process and the influence of pH and buffer type on the stability and activity of the IMERs have been investigated. The resulting T. cruzi GAPDH-IMER was coupled to an analytical octyl column, which was used to achieve chromatographic separation of NAD(+) from NADH. The production of NADH stimulated by d-glyceraldehyde-3-phosphate was used to investigate the activity and kinetic parameters of the immobilized T. cruzi GAPDH. The Michaelis-Menten constant (K(m)) values determined for d-glyceraldehyde-3-phosphate and NAD(+) were K(m) = 0.5 +/- 0.05 mM and 0.648 +/- 0.08 mM, respectively, which were consistent with the values obtained using the non-immobilized enzyme. 相似文献